RAPUANO, Karen M. (DeMartino) of Charlestown, entered into eternal rest on Thursday, January 19, 2023 in the Kaplan Family Hospice House in Danvers after being in failing health.  She was born in Boston and resided in Charlestown.  Karen worked at the Beth Israel Lahey Medical Center as their Director of Information Technology.  Beloved wife of Michael Rapuano for over 37 years.  Loving daughter of the late Achilles and Antoinette (Tarallo) DeMartino.  Dear and devoted sister of Michael DeMartino and his wife, Lidia of Canton and Robert DeMartino and his wife, Peggy of  Norton. Relatives and friends are respectfully invited to attend Karen's funeral Mass in St. Mary's Church, 55 Warren St., Charlestown, Friday, Jan. 27 at 10 a.m.  Interment Private.  In lieu of flowers, contributions in Karen's memory to St. Jude Children's Research Hospital, 501 St. Jude Place, Memphis TN. 38105 would sincerely appreciated.   Arrangements by the Cafasso & Sons Funeral Home, Everett.